PENTACYCLIC TRITERPENE GLYCOSIDE COMPOUND, METHOD FOR PRODUCTION AND USE THEREOF Russian patent published in 2025 - IPC C07J63/00 A61K31/58 A61P1/16 A61P3/00 A61P3/04 A61P31/16 

FIELD: chemistry.

SUBSTANCE: present invention relates to a pentacyclic C-glycoside derivative, methods for preparing it and use thereof. In particular, the present invention relates to a compound of general formula II or III, or a pharmaceutically acceptable salt thereof: . In formulas II and III, ring A is selected from a group consisting of 6-membered saturated carbocyclic ring or unsaturated carbocyclic ring; R₁, R₂ and R₃ each is independently selected from the group consisting of hydrogen and a methyl group; R₄ is selected from the group consisting of hydrogen and an isopropenyl group; R₅ is selected from a group consisting of a carboxyl group, substituted or unsubstituted C₂-C₁₀ ester group, substituted or unsubstituted C₁-C₆ amide group and Y-R₇; where, Y is selected from a group consisting of -(CH₂)_mCHR₉-, carbonyl group, and -COO-; m is 0 or 1; Z is selected from a group consisting of a carbonyl group, -C(R₉)₂, C=N-R₈, C=N-NH-R₈; X is selected from a group consisting of -CHR₉-, a carbonyl group, S, -NHC (O) -R₈, -NHS(O)₂-R₈, -NHC(O)NH-R₈, - NHC(S)NH-R₈, and -OS(O)₂-R₈; n is 1 or 2. Values R₆-R₉ such as are indicated in the claim.

EFFECT: development of new pentacyclic triterpene C-glycosides, which are used for preparation of medicinal agent for treatment or prevention of metabolic or viral diseases.

13 cl, 10 dwg, 3 tbl, 236 ex