METHOD OF REDUCING ALDEHYDES AND KETONES Russian patent published in 2025 - IPC C07C29/141 C07C29/145 C07C31/02 C07C35/08 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of reducing aldehydes and ketones to form alcohols. Method consists in continuous passage of substrate and hydrogen at atmospheric pressure and temperature of 20-80 °C through a catalyst layer – nickel nanoparticles deposited on aluminium oxide. Passage is carried out at consumption of substrate and hydrogen of 0.5 ml/h and 2 l/h, respectively. Nickel nanoparticles are applied by impregnating aluminium oxide while boiling until decolouration with a solution of nickel chloride hexahydrate and carbamide in 7 wt.% aqueous ammonia solution, adding boric acid and boiling for 2 hours. Weight ratio of aluminium oxide : hexahydrate of nickel chloride : carbamide : boric acid is 1:2:2.4:0.6. Then, adsorbed nickel chloride is reduced at temperature of 80-100 °C for 1 hour with mixture of 0.025 wt.% aqueous solution of sodium borohydride and hydrazine monohydrate, taken in molar ratio of 4:3. Immediately before the reaction, the catalyst is dried in a stream of hydrogen at 350-400 °C.

EFFECT: higher yield of products.

1 cl, 10 ex