METHOD OF PRODUCING 1-(3-(TRIMETHOXYSILYL)PROPYL)BENZIMIDAZOLE Russian patent published in 2025 - IPC C07F7/18 

Abstract RU 2833785 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organosilicon chemistry and is a method of producing 1-(3-(trimethoxysilyl)propyl)benzimidazole, used for synthesis of immobilized ionic liquids, obtaining films on metal surfaces as an intermediate product in synthesis of biologically active compounds. Method is carried out in one reactor in two steps. At the first step, a sodium salt of benzimidazole is obtained by heating equimolar amounts of benzimidazole and sodium hydroxide in a toluene medium with water separation. Half of the used toluene is then distilled off, dimethylformamide is added to the reaction mass and the sodium salt of benzimidazole is alkylated with (3-chloropropyl)trimethoxysilane while heating for 3 hours at the boiling point of the reaction mass.

EFFECT: improved method of producing 1-(3-(trimethoxysilyl)propyl)benzimidazole using readily available starting reagents and a solvent which provides high output of the end product.

1 cl, 1 ex

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RU 2 833 785 C1

Authors

Konshin Valerii Viktorovich

Spesivaia Ekaterina Sergeevna

Sharafan Mikhail Vladimirovich

Konshina Dzhamilia Naibovna

Dates

2025-01-28Published

2024-06-14Filed