FIELD: biotechnology.
SUBSTANCE: group of inventions relates to biotechnology and can be used in medicine. Invention discloses methods of producing an isolated population of immune cells not inducing a graft-versus-host reaction (GVHD), having a central memory T-lymphocyte (Tcm) phenotype, wherein said cells are tolerance-inducing cells and/or have disease activity, and are also capable of returning to lymph nodes after transplantation.
EFFECT: disclosed are antiviral veto cells of central memory CD8+ in haploidentical stem cell transplantation.
24 cl, 3 ex, 6 tbl, 8 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| VETO-CELLS OBTAINED FROM MEMORY T-CELLS | 2017 |
|
RU2779844C2 |
| CENTRAL MEMORY T-CELLS OF AGAINST THIRD PARTY, METHODS FOR THEIR PRODUCTION AND THEIR APPLICATION IN TRANSPLANTATION AND DISEASES TREATMENT | 2012 |
|
RU2636503C2 |
| ANTI THIRD PARTY CENTRAL MEMORY T CELLS, METHODS FOR PRODUCTION THEREOF AND USE THEREOF IN TRANSPLANTATION AND DISEASE TREATMENT | 2009 |
|
RU2506311C2 |
| COMBINATION THERAPY FOR STABLE AND LONG TERM ENGRAFTMENT USING SPECIFIC PROTOCOLS FOR T/B-CELL DEPLETION | 2012 |
|
RU2648354C2 |
| COMBINATION THERAPY FOR STABLE AND LONG-TERM TRANSPLANT ENGRAFTMENT | 2012 |
|
RU2657758C2 |
| UNIVERSAL ANTIGEN PRESENTING CELLS AND THEIR USE | 2019 |
|
RU2809113C2 |
| T CELL RECEPTOR-DEFICIENT T CELL COMPOSITIONS | 2013 |
|
RU2653761C2 |
| METHODS OF INCREASING EFFICIENCY OF DEPLETION OF TCRαβ+ CELLS | 2020 |
|
RU2829624C2 |
| METHODS FOR PRODUCING ALLOGENIC T-CELLS WITH CAR | 2020 |
|
RU2828787C2 |
| NEW SUBPOPULATION OF TREG CD8CD45RC CELLS AND ITS APPLICATIONS | 2016 |
|
RU2766691C2 |
