PREVENTIVE AND/OR THERAPEUTIC AGENT FOR CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME Russian patent published in 2025 - IPC A61K31/343 A61K31/416 A61K31/4184 A61K31/423 A61P13/08 

Abstract RU 2836236 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions relates to pharmaceutical industry, namely to use of mPGES-1 inhibitor for preparing a drug for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome. Disclosed is the use of the mPGES-1 inhibitor for the manufacture of a medicinal agent for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome, where the mPGES-1 inhibitor is: compound selected from a group consisting of N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide and N-(3-chloro-2-methylphenyl)-2-[1-(trifluoromethyl)cyclopropyl]-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide or a tautomer of a compound, or a pharmaceutically acceptable salt thereof; N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide 4-methylbenzene sulphonate; N-(3-chloro-2-methylphenyl)-2-[1-(trifluoromethyl)cyclopropyl]-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide.

EFFECT: described above mPGES-1 inhibitors are effective for preparing a drug for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome.

3 cl, 1 dwg, 1 tbl, 8 ex

Similar patents RU2836236C1

Title Year Author Number
HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL MEANS 2012
  • Otsu Khironori
RU2632908C2
HETEROCYCLIC DIHYDROPYRIMIDINE COMPOUNDS 2000
  • Ehtuol Karnehjl S.
  • Vakkaro Uehjn
  • Llojd Dzhon
  • Finlej Khizer
  • Jan Lin S.
  • Bkhandaru Rao
RU2296766C2
USE OF EP4 RECEPTOR ANTAGONIST IN TREATMENT OF CARTILAGE DISEASE 2014
  • Okumura Takako
RU2663620C2
N-((HET)ARYLMETHYL)-HETEROARYL-CARBOXAMIDE COMPOUNDS AS PLASMA KALLIKREIN INHIBITORS 2015
  • Dejvi, Rebekka Luiz
  • Edvards, Khannakh Dzhoj
  • Evans, Devid Majkl
  • Khodgson, Sajmon Tinbi
RU2821520C2
BICYCLIC DIHYDROPYRIMIDINECARBOXAMIDE DERIVATIVES AS RHO-KINASE INHIBITORS 2017
  • Accetta, Alessandro
  • Rancati, Fabio
  • Capelli, Anna Maria
  • Clark, David Edward
  • Tisselli, Patrizia
  • Edwards, Christine
  • Bhalay, Gurdip
RU2778478C2
USING EP4 RECEPTOR LIGANDS IN TREATMENT OF IL-6-MEDIATED DISEASES 2003
  • Simodzo Masato
  • Taniguti Kana
RU2285527C2
N-((HET)ARYLMETHYL)-HETEROARYL-CARBOXAMIDE COMPOUNDS AS PLASMA KALLIKREIN INHIBITORS 2015
  • Hodgson, Simon Teanby
  • Evans, David Michael
  • Edwards, Hannah Joy
  • Davie, Rebecca Louise
RU2707870C2
PYRAZOLPYRIMIDINE COMPOUNDS JAK INHIBITORS AND METHODS 2009
  • Blehjni Dzheffri
  • Gibbons Pol A.
  • Khanan Ehmili
  • Lissikatos Dzhozef P.
  • Magnuson Stiven R.
  • Pastor Richard
  • Rouson Tomas E.
  • Chzhou Ajkheh
  • Chzhu Bin-Jan'
RU2539568C2
HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS 2005
  • Bauehr Dzhastin Fehrfild
  • Pojser Dzheffri Filip
  • Terner Pol
  • Uoterson Dehvid
  • Uinter Dzhon
RU2423349C2
AZASPIROALKANE DERIVATIVES METALLOPROTEASE INHIBITORS 2004
  • Jao Vehn'Tsin
  • Chzho Tszin'Tsun
  • Ksu Mehjchzhun
  • Chzhan Fehnlehj
  • Metkaf Brajan
RU2379303C2

RU 2 836 236 C1

Authors

Okamoto Ken

Kurita Maki

Yamaguchi Hiroshi

Dates

2025-03-11Published

2020-12-24Filed