FIELD: medicine; pharmaceutics.
SUBSTANCE: group of inventions relates to pharmaceutical industry, namely to use of mPGES-1 inhibitor for preparing a drug for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome. Disclosed is the use of the mPGES-1 inhibitor for the manufacture of a medicinal agent for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome, where the mPGES-1 inhibitor is: compound selected from a group consisting of N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide and N-(3-chloro-2-methylphenyl)-2-[1-(trifluoromethyl)cyclopropyl]-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide or a tautomer of a compound, or a pharmaceutically acceptable salt thereof; N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide 4-methylbenzene sulphonate; N-(3-chloro-2-methylphenyl)-2-[1-(trifluoromethyl)cyclopropyl]-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide.
EFFECT: described above mPGES-1 inhibitors are effective for preparing a drug for preventing and/or treating chronic prostatitis/chronic pelvic pain syndrome.
3 cl, 1 dwg, 1 tbl, 8 ex
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Authors
Dates
2025-03-11—Published
2020-12-24—Filed