METHOD OF PRODUCING COMPOSITE NONWOVEN POLYMER MATERIAL FOR BONE TISSUE REGENERATION Russian patent published in 2025 - IPC A61L27/58 A61L27/46 A61L27/18 A61L27/12 C08J5/00 C08G63/08 C08K3/32 C08L101/16 

FIELD: chemistry.

SUBSTANCE: invention relates to chemistry, more specifically to polymer materials for medical purposes. Disclosed is a method of producing a composite nonwoven polymer material for bone tissue regeneration, according to which poly(L-lactide) granules are dissolved in trichloromethane to obtain a polymer solution with concentration of 3 wt.%, after which the obtained polymer solution is held for 48 hours under normal conditions, then 30 vol.% of acetone from the volume of said solution and 10-30 wt.% of hydroxyapatite powder from the weight of poly(L-lactide) are added to the polymer solution, obtained mixture is homogenised in an ultrasonic bath to a homogeneous state and then used for electrospinning with a spinneret electrode in the form of a needle and a deposition electrode in the form of a rotating shaft at a distance between the needle and the deposition electrode of 180 mm, a flow rate of mixture of 6 ml/h, voltage of 20 kV, an inner diameter of needle of 0.413 mm and a rotation speed of a rotating shaft with diameter of 100 mm – 50 rpm.

EFFECT: invention enables to obtain a mechanically resistant and strong material consisting of fibres with thickness of 0.6 to 43.7 mcm and characterized by thickness of 130-330 mcm, a tensile strength of 3.4-23 MPa, a maximum tensile elongation of 28-70% and an edge wetting angle 98-135°.

3 cl, 3 dwg, 3 ex