FIELD: chemistry.
SUBSTANCE: present invention relates to chemistry of high-molecular compounds for biomedical purposes. Described are water-soluble copolymers of hydroxycinnamic acid and vinyl monomers with activity on influenza virus and herpes simplex virus of general formula: An – Bm, where: A and B are polymer links; A is a link of hydroxycinnamic acid; B is a vinyl comonomer link; n and m are content of A and B, mol. %, n=8-46, m=100-n, with molecular weight 103÷105, obtained by radical copolymerisation in a mass or organic solvent of coumarin with vinyl comonomers, followed by alkaline hydrolysis of coumarin links, where the residue of the vinyl comonomer is taken from: sodium styrene sulphonate, acrylic, methacrylic acid, acrylamide.
EFFECT: obtaining water-soluble copolymers which can be used as a base for preparing effective antiviral drugs.
1 cl, 6 tbl, 18 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COPOLYMERS OF N-VINYLAMIDES WITH SALTS OF HYDROXYCINNAMIC ACID | 2022 |
|
RU2796753C1 |
| WATER-SOLUBLE SULPHONATED POLYMERS WITH INTRINSIC ANTIVIRAL ACTIVITY AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2814298C1 |
| METHOD OF PRODUCING WATER-SOLUBLE COPOLYMERS OF N-VINYL AMIDES CONTAINING ALDEHYDE GROUPS | 2015 |
|
RU2594253C1 |
| METHOD FOR PREPARING WATER-SOLUBLE HOMOPOLYMERS AND COPOLYMERS OF VINYLAMINE | 2002 |
|
RU2243977C2 |
| METHODS OF PRODUCING METHACRYLOYLGUANIDINE SALT, POLYMER AND COPOLYMER OF METHACRYLOYLGUANIDINE SALT AND PRODUCED POLYMER AND COPOLYMER | 2016 |
|
RU2669563C2 |
| POLYMERIC WATER-SOLUBLE DERIVATIVES OF 4-PHENYLBUTANOIC ACID HAVING ANTI-TUMOUR ACTIVITY | 2016 |
|
RU2635539C2 |
| METHOD OF PRODUCING SYNTHETIC METAL-POLYMER COMPLEXES OF RADIOISOTOPE GALLIUM-68 | 2015 |
|
RU2588144C1 |
| METHOD OF PRODUCING WATER-SOLUBLE POLYMER COMPLEXES | 2024 |
|
RU2839245C1 |
| COPOLYMER BASED ON N,N-DIALLYLAMINOBUTANEDIOIC ACID AND VINYLACETATE | 2013 |
|
RU2537395C2 |
| COPOLYMER BASED ON N,N-DIALLYLAMINOETHANOIC ACID AND VINYL ACETATE | 2011 |
|
RU2466148C1 |
