METHOD OF HEME-COMPATIBLE POLYMERIC HYDROGEL PRODUCING Russian patent published in 1998 - IPC

Abstract SU 1078894 A1

FIELD: biotechnology, polymers. SUBSTANCE: method involves acylation of heparin with acrylic or methacrylic acid chloroanhydride in an aqueous solution followed by addition of acrylamide, bifunctional monomer-cross-linking agent and carrying out the initiated radical copolymerization. Method involves also the additional addition of trypsin acylated with acrylic or methacrylic acid chloroanhydride to reaction solution at weight ratio of acylated heparin : acylated trypsin = (10-50):1. EFFECT: increased heme-compatibility of hydrogels.

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SU 1 078 894 A1

Authors

Plateh N.A.

Burdygina I.F.

Chupov V.V.

Valuev L.I.

Dates

1998-01-10—Published

1982-04-23—Filed