AFFINE ADSORBENT FOR REMOVAL OF BILIRUBIN AND OTHER TOXICANTS FROM BLOOD AND A METHOD OF ITS PRODUCING Russian patent published in 1998 - IPC

Abstract SU 731750 A1

FIELD: biotechnology. SUBSTANCE: affine adsorbent has albumin covalently immobilized on polymeric carrier and water. Adsorbent has 10-40 weight % copolymer of albumin acylated with unsaturated acid chloroanhydride as immobilized albumin, N-vinylpyrrolidone and bifunctional cross-linking agent. To produce adsorbent albumin acylated with unsaturated acid chloroanhydride (5-20 weight%) is polymerized in water with 5-20 weight % a mixture consisting of N-vinylpyrrolidone and bifunctional cross-linking agent at weight ratio of monomers in mixture and cross-linking agent = (9-7):(1-3). EFFECT: increased capacity and heme-biocompatibility of adsorbent, decreased hypoproteinemia.

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SU 731 750 A1

Authors

Plateh N.A.

Valuev L.I.

Vakula A.V.

Akopjan V.G.

Kondakov V.T.

Dates

1998-01-10—Published

1978-12-21—Filed