METHOD OF OBTAINING THROMBORESISTANT POLYMER MATERIAL Russian patent published in 2015 - IPC A61L27/50 A61L27/14 A61L29/14 A61L33/12 C08F255/00 C08F265/04 C08F283/00 

Abstract RU 2556996 C1

FIELD: chemistry.

SUBSTANCE: thromboresistant polymer material is obtained by radiation grafting copolymerisation of mixture of hydrophilic monomer and unsaturated biologically active compound on the surface of polymer material with weight ratio hydrophilic monomer:unsaturated active compound 1:0.2-1:1. Mixture of hirudin, acylated with acrylic acid chloranhydride, and ovomucoid from duck egg white, acylated with acrylic acid chloranhydride in ratio 1:0.8-1:2 is used as unsaturated biologically active compound.

EFFECT: reduction of quantity of platelets adhered on the surface of material with preservation of reduced ability to blood clotting on the surface of material.

1 tbl, 11 ex

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RU 2 556 996 C1

Authors

Valuev Ivan L'Vovich

Vanchugova Ljudmila Vital'Evna

Obydennova Irina Vasil'Evna

Valuev Lev Ivanovich

Talyzenkov Jurij Afanas'Evich

Dates

2015-07-20Published

2014-03-06Filed