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2 556 996

(13)

(51)

IPC

A61L27/50(2006-01-01)

A61L27/14(2006-01-01)

A61L29/14(2006-01-01)

A61L33/12(2006-01-01)

C08F255/00(2006-01-01)

C08F265/04(2006-01-01)

C08F283/00(2006-01-01)

(21) (22)

Application

2014108502/04, 2014-03-06

(24)

Start date

2014-03-06

(22)

Actual filing date

2014-03-06

(45)

Published

2015-07-20

(72)

Inventor

Valuev Ivan L'VovichVanchugova Ljudmila Vital'EvnaObydennova Irina Vasil'EvnaValuev Lev IvanovichTalyzenkov Jurij Afanas'Evich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Ordena Trudovogo Krasnogo Znameni Institut Neftekhimicheskogo Sinteza Im. A.V. Topchieva Rossijskoj Akademii Nauk Ran)

METHOD OF OBTAINING THROMBORESISTANT POLYMER MATERIAL Russian patent published in 2015 - IPC A61L27/50 A61L27/14 A61L29/14 A61L33/12 C08F255/00 C08F265/04 C08F283/00

Abstract RU 2556996 C1

FIELD: chemistry.

SUBSTANCE: thromboresistant polymer material is obtained by radiation grafting copolymerisation of mixture of hydrophilic monomer and unsaturated biologically active compound on the surface of polymer material with weight ratio hydrophilic monomer:unsaturated active compound 1:0.2-1:1. Mixture of hirudin, acylated with acrylic acid chloranhydride, and ovomucoid from duck egg white, acylated with acrylic acid chloranhydride in ratio 1:0.8-1:2 is used as unsaturated biologically active compound.

EFFECT: reduction of quantity of platelets adhered on the surface of material with preservation of reduced ability to blood clotting on the surface of material.

1 tbl, 11 ex

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RU 2 556 996 C1

Authors

Valuev Ivan L'Vovich

Vanchugova Ljudmila Vital'Evna

Obydennova Irina Vasil'Evna

Valuev Lev Ivanovich

Talyzenkov Jurij Afanas'Evich

Dates

2015-07-20—Published

2014-03-06—Filed