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731 752

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A1

(51)

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Application

2704357/05, 1978-12-12

(22)

Actual filing date

1978-12-12

(45)

Published

1998-01-10

(72)

Inventor

Plateh N.A.Valuev L.I.Vakula A.V.Gumirova F.Kh.Akopjan V.G.Kondakov V.T.

AFFINE ADSORBENT FOR REMOVAL OF BILIRUBIN AND OTHER TOXICANTS FROM BLOOD AND A METHOD OF ITS PRODUCING Russian patent published in 1998 - IPC

Abstract SU 731752 A1

FIELD: biotechnology, sorbents. SUBSTANCE: adsorbent has copolymer of albumin and heparin acylated with unsaturated acid chloroanhydride (10.5-18 weight%) as covalently bound albumin, N-vinylpyrrolidone or acrylamide and bifunctional cross-linking agent. To produce adsorbent albumin acylated with unsaturated acid chloroanhydride (5-15 weight %), heparin acylated with unsaturated acid chloroanhydride (0.5-3 weight %) and a mixture consisting of N-vinylpyrrolidone or acrylamide and bifunctional agent (5-15 weight%) were polymerized at weight ratio of monomer in mixture and cross-linking agent = (1-20): 1. EFFECT: increased capacity and heme-compatibility of adsorbent, elimination of lability of chemical and biological properties of adsorbent.

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SU 731 752 A1

Authors

Plateh N.A.

Valuev L.I.

Vakula A.V.

Gumirova F.Kh.

Akopjan V.G.

Kondakov V.T.

Dates

1998-01-10—Published

1978-12-12—Filed

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