FIELD: medicine, organic chemistry. SUBSTANCE: desired product is prepared by interaction of 2-mercapto-4-phenyl imidazole and hydrobromide of 2-morpholinoethyl bromide. The process is carried out in the medium of NaOH. Thus obtained product is mixed with isopropanol, then HCl and ether are added. Yield of desired product is 62.6 %, its melting point being 246 C. EFFECT: improves quality of desired product. 1 tbl
| Title |
Year |
Author |
Number |
| 4-(4'-METHOXYPHENYL)-2-MORPHOLINOETHYLTHIO-5-PHENYLIMIDAZOLE DIHYDROCHLORIDE ENHANCING PHYSICAL RESISTANCE |
1986 |
- Vinogradov V.M.
- Tomchin A.B.
- Spivakova R.P.
- Katkov V.F.
|
SU1415725A1 |
| DIHYDROCHLORIDE OF 4-(4′-BROMOPHENYL)-2-MORPHOLINOETHYLTHIO-5-PHENYL IMIDAZOLE HAVING PROTECTING ACTIVITY AGAINST STRESS |
1985 |
- Tomchin A.B.
- Vinogradov V.M.
- Khromenkova Z.A.
- Katkov V.F.
- Katkova E.B.
|
SU1387374A1 |
| DIHYDROCHLORIDE OF 2-MORPHOLINO-ETHYLTHIO-4,5-DI-(P-CHLOROPHENYL)IMIDAZOLE HAVING ACTIVITY AGAINST HYPOXIA |
1985 |
- Tomchin A.B.
- Vinogradov V.M.
- Khromenkova Z.A.
- Katkov V.F.
|
SU1279212A1 |
| DIHYDROCHLORIDE OF 2-MORPHOLINOETHYLTHIO-4,5-DIPHENYL IMIDAZOLE HAVING ACTIVITY AGAINST HYPOXIA AND ACCELERATING PROCESSES OF REDUCTION AFTER PHYSICAL LOAD AND PROLONGED STRESS |
1984 |
- Tomchin A.B.
- Vinogradov V.M.
- Katkov V.F.
- Basieva T.S.
- Smirnov A.V.
- Bobkov Ju.G.
- Lozinskij M.O.
- Katkova E.B.
|
SU1220306A1 |
| DIHYDROCHLORIDE OF 4,5-DI-(3′,4′-DIMETHOXYPHENYL)-2-MORPHOLINOETHYLTHIO IMIDAZOLE HAVING ACTIVITY AGAINST HYPOXIA |
1985 |
- Tomchin A.B.
- Vinogradov V.M.
- Khromenkova Z.A.
- Katkov V.F.
- Katkova E.B.
|
SU1295709A1 |
| 8-METHYL-3-(2-MORPHOLINOETHYLTHIO)-5H-1,2,4-TRIAZINO[5,6-B]INDOLE DIHIDROCHLORIDE HYDRATE SHOWING CAPABILITY TO ACCELERATE RECOVERY OF CEREBRUM FUNCTION IN THE EARLY PERIOD AFTER ACUTE MICROWAVE THERMAL STRESS |
1990 |
- Grechko A.T.
- Tomchin A.B.
- Lomov O.P.
- Smirnov A.V.
|
RU1764298C |
| DIHYDROCHLORIDE OF 2-(2-MORPHOLINOETHYLTHIO)-5-ETHOXYBENZIMIDAZOLE WHICH ACCELERATES PROCESSES OF REDUCTION AFTER PHYSICAL LOAD |
1984 |
- Tomchin A.B.
- Dmitrukha V.S.
- Vinogradov V.M.
- Spivakova R.P.
- Katkov V.F.
- Bobkov Ju.G.
|
SU1262926A1 |
| 8-METHOXY-3-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]- INDOLE MALATE SHOWING ANTIHYPOXIC ACTIVITY |
1988 |
- Tomchin A.B.
- Marysheva V.V.
- Katkov V.F.
- Urjupov O.Ju.
- Kostycheva M.V.
- Smirnov A.V.
|
SU1547280A1 |
| DIHYDROCHLORIDE OF MONOHYDRATE OF 8-BROMO-3-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO/5,6-B/INDOLE HAVING PROTECTING ACTIVITY AGAINST STRESS AND INCREASING PHYSICAL RESISTANCE |
1984 |
- Tomchin A.B.
- Vinogradov V.M.
- Katkov V.F.
- Spivakova R.P.
- Smirnov A.V.
- Katkova E.B.
- Lozinskij M.O.
- Bobkov Ju.G.
|
SU1220301A1 |
| 2-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO(6,5-b)INDOL HYDROCHLORIDE POSSESSING ANTIHYPOXIC AND ANTIINFLAMMATORY ACTIVITY |
1981 |
- Tomchin A.B.
- Vinogradov V.M.
- Basieva T.S.
- Poskalenko A.N.
- Ponomareva M.M.
|
SU1014250A1 |
