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1 450 373

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Application

4249707/13, 1987-05-25

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Actual filing date

1987-05-25

(45)

Published

1995-06-09

(72)

Inventor

Kudinova M.K.Murenets N.V.Vasil'Eva Ju.V.Korobkova T.P.Drobysheva T.N.Ivanova T.A.Ivanitskaja L.P.

METHOD OF OMOMYCIN PREPARING Russian patent published in 1995 - IPC

Abstract SU 1450373 A1

FIELD: microbiological industry. SUBSTANCE: for omomycin preparing strain Streptomyces chromopurpureus subsp. chiketamanus subsp. nov. 985 is cultured. Then cultural fluid or separated mycelium is dried and extracted with a mixture of petroleum ether and chloroform or methylene chloride at the ratio of the latter 3-4:1. Then extract is concentrated under vacuum, and chromatographic purification is carried out on the column with aqueous silicic acid. Yield of omomycin is 80-85% of its content in cultural fluid at 85-90% purification degree. EFFECT: simplified method.

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SU 1 450 373 A1

Authors

Kudinova M.K.

Murenets N.V.

Vasil'Eva Ju.V.

Korobkova T.P.

Drobysheva T.N.

Ivanova T.A.

Ivanitskaja L.P.

Dates

1995-06-09—Published

1987-05-25—Filed

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