FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: product: 3-(3-dimethylaminopropylthio)-1,2,4-triazino-[5,6-b] -indole hydrochloride. Synthesis is carried out from 3-mercapto-1,2,4-triazino-[5,6-b]-indole solution in 1N NaOH aqueous solution and 3-dimethylaminopropyl-chloride hydrochloride. Yield is 77.6%, m. p. is 223 C, LD50 = 560 mg/kg. EFFECT: detection of compounds with enhanced activity. 1 tbl
| Title |
Year |
Author |
Number |
| (1,2,4-TRIAZINO-[5,6-B]-INDOLYL-3-THIO)-ACETIC ACID N-(2-HYDROXYETHYL)-AMIDE SHOWING ANTIHYPOXIC ACTIVITY AND RECOVERING FUNCTIONAL ELECTRIC BRAIN ACTIVITY |
1991 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Urjupov O.Ju.
- Katkov V.F.
- Mostycheva M.V.
- Smirnov A.V.
- Pavlovskij V.F.
|
SU1804067A1 |
| 3-(PIPERIDINOCARBONYLMETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE SHOWING ANTIHYPOXIC ACTIVITY AND PROTECTING AGAINST ACUTE TOXIC LUNG EDEMA |
1989 |
- Zhukova T.I.
- Kuznetsova T.A.
- Tomchin A.B.
- Urjupov O.Ju.
- Kostycheva M.V.
- Kropotov A.V.
- Butakov V.N.
|
SU1681504A1 |
| 3-(2-DIMETHYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLYL-5- ACETAMIDE PROTECTING AGAINST ACUTE TOXIC LUNG EDEMA |
1989 |
- Tomchin A.B.
- Kropotov A.V.
- Butakov V.N.
- Urjupov O.Ju.
- Kostycheva M.V.
- Marysheva V.V.
|
SU1674533A1 |
| AMIDE OF (1,2,4-TRIAZINO[5,6-B]INDOLYL-3-THIO)ACETIC ACID WHICH ACCELERATES PROCESSES OF REDUCTION AFTER PHYSICAL LOAD AND HAS ACTIVITY AGAINST HYPOXIA |
1987 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Vinogradov V.M.
- Spivakova R.P.
- Urjupov O.Ju.
- Kostycheva M.V.
|
SU1487413A1 |
| (1,2,4-TRIAZINO-[5,6-B]-INDOLYL-3-THIO)-ACETIC ACID DIETHYLAMIDE SHOWING ANTIHYPOXIC ACTIVITY |
1989 |
- Zhukova T.I.
- Kuznetsova T.A.
- Tomchin A.B.
- Urjupov O.Ju.
- Kostycheva M.V.
- Smirnov A.V.
|
SU1665679A1 |
| 3-(MORPHOLINOCARBONYLMETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE ENHANCING RESISTANCE TO HYPERCAPNIC HYPOXIA |
1989 |
- Turzhova E.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Tomchin A.B.
|
SU1596719A1 |
| HYDROCHLORIDE OF 3-(2-DIETHYLAMINOETHYLAMINO0-1,2,4-TIAZINO/5,6-B/INDOLE INCREASING RESISTANCE OF ORGANISM AGAINST HYPOXIA |
1981 |
- Tomchin A.B.
- Basieva T.S.
- Vinogradov V.M.
- Pastushenkov L.V.
- Urjupov O.Ju.
|
SU978567A1 |
| 3-(3-MORPHOLINOPROPYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE RECOVERING PHYSICAL ENDURANCE AFTER POISONING WITH ORGANOPHOSPHORUS PESTICIDE |
1988 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Kalinina I.B.
- Spivakova R.P.
- Tonkopij D.V.
- Smirnov A.V.
|
SU1584352A1 |
| DIHYDROCHLORIDE OF 3-(2-DIMETHYLAMINO)ETHYLAMINO-1,2,4-TRIAZINO(5,6-B)INDOLE IMPROVING RESISTANCE OF ORGANISM AGAINST HYPOXIA |
1984 |
- Tomchin A.B.
- Vinogradov V.M.
- Basieva T.S.
- Makeev B.L.
|
SU1235181A1 |
| HYDROCHLORIDE OF 3-(2-DIPROPYLAMINOETHYLTHIO)-1,2,4-TRIAZINO[5,6-B)-INDOLE WHICH INCREASES RESISTANCE AGAINST HYPERTERMIA |
1987 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Zvezdina N.S.
- Vinogradov V.M.
- Katkov V.F.
- Sumina Eh.N.
- Katkova E.B.
- Andreev V.B.
|
SU1483895A1 |
