FIELD: medicine and pharmacology. SUBSTANCE: desired product: 8-amino-3- (2-diethylaminoethylthio) -1,2,4- triazino [5,6-b] -indol hydrochloride. Empirical formula: C15H21SN6Cl. Yield: 68 %. Melting point: 238 C. Reagent No. 1: 8-amino -2,3- dihydro -1,2,4-triazino[5,6-b] indolthione-3. Reagent No. 2: hydrobromide -2- diethylamino -ethylbromide. Reaction conditions: aqueous medium in presence of alkali excess. EFFECT: excellent remedy promoting recovery of encephalon functions after acute microwave thermal stress. 2 tbl
| Title |
Year |
Author |
Number |
| 8-METHYL-3-(2-MORPHOLINOETHYLTHIO)-5H-1,2,4-TRIAZINO[5,6-B]INDOLE DIHIDROCHLORIDE HYDRATE SHOWING CAPABILITY TO ACCELERATE RECOVERY OF CEREBRUM FUNCTION IN THE EARLY PERIOD AFTER ACUTE MICROWAVE THERMAL STRESS |
1990 |
- Grechko A.T.
- Tomchin A.B.
- Lomov O.P.
- Smirnov A.V.
|
RU1764298C |
| 5-(2-MORPHOLINOETHYL) -3-N-BUTYLTHIO -5H-1,2,4- TRIAZINO- [5,6-B] INDOLE HYDROCHLORIDE SHOWING CAPABILITY TO RECOVERY FUNCTIONS OF ORGANISM AND NORMALIZE BEHAVIORAL ACTIVITY AT THE EARLY PERIOD AFTER ACUTE MICROWAVE THERMAL STRESS |
1990 |
- Grechko A.T.
- Tomchin A.B.
- Lomov O.P.
- Smirnov A.V.
|
SU1764297A1 |
| 8-AMINO-3-(2-DIPROPYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-5,6-INDOLE HYDROCHLORIDE ACCELERATING RECOVERY OF BRAIN FUNCTIONS AT THE EARLY PERIOD AFTER ACUTE MICROWAVE THERMAL STRESS |
0 |
- Tomchin Aleksandr Beniaminovich
- Grechko Aleksandr Timofeevich
- Smirnov Aleksandr Vladimirovich
|
SU1825794A1 |
| 3-(3-MORPHOLINO-2-OXYPROPYLTHIO)-1,2,4-TRIAZINO[5,6-B]INDOLE WHICH ACCELERATES PROCESSES OF REDUCTION AFTER PHYSICAL LOAD |
1986 |
- Tomchin A.B.
- Spivakova R.P.
- Vinogradov V.M.
- Timofeeva E.B.
|
SU1420901A1 |
| 3-(2-DIMETHYLAMINOETHYLTHIO)-8-METHYL-1,2,4-TRIAZINO-[5,6-B]- INDOLE DIHYDROCHLORIDE ENHANCING RESISTANCE TO HYPERTHERMIA |
1988 |
- Tomchin A.B.
- Katkov V.F.
- Sumina Eh.N.
- Katkova E.B.
- Kravchenko V.V.
|
SU1547279A1 |
| 8-BROMO-3-(2-DIETHYLAMINOETHYLTHIO)-1,2,4-TRIAZINO(5,6-B)INDOLE WHICH ACCELERATES PROCESSES OF REDUCTION AFTER PHYSICAL LOAD AND PROLONGED STRESS |
1984 |
- Tomchin A.B.
- Vinogradov V.M.
- Katkov V.F.
- Spivakova R.P.
- Krylova I.M.
- Katkova E.B.
|
SU1223608A1 |
| 3-(2-DIMETHYLAMINOETHYLTHIO)-8-METHOXY-1,2,4-TRIAZINO-[5,6-B]- INDOLE DIHYDROCHLORIDE ENHANCING RESISTANCE TO HYPERTHERMIA |
1988 |
- Tomchin A.B.
- Katkov V.F.
- Sumina Eh.N.
- Katkova E.B.
- Krjukova L.M.
- Zelenin K.N.
|
SU1552605A1 |
| HYDROCHLORIDE OF 3-(2-DIMETHYLAMINOETHYLTHIO)-9-METHYL-1,2,4-TRIAZINO(6,5-B)INDOLE WHICH INCREASES PHYSICAL RESISTANCE |
1981 |
- Tomchin A.B.
- Vinogradov V.M.
- Spivakova R.P.
- Basieva T.S.
|
SU1061424A1 |
| HYDROCHLORIDE OF 3-(2-DIPROPYLAMINOETHYLTHIO)-1,2,4-TRIAZINO[5,6-B)-INDOLE WHICH INCREASES RESISTANCE AGAINST HYPERTERMIA |
1987 |
- Tomchin A.B.
- Zhukova T.I.
- Kuznetsova T.A.
- Zvezdina N.S.
- Vinogradov V.M.
- Katkov V.F.
- Sumina Eh.N.
- Katkova E.B.
- Andreev V.B.
|
SU1483895A1 |
| 3-(2-DIETHYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLYL-5- ACETAMIDE HYDROCHLORIDE ACCELERATING RECOVERY PROCESS AFTER PHYSICAL LOADING |
1989 |
- Tomchin A.B.
- Spivakova R.P.
- Smirnov A.V.
|
SU1623156A1 |
