FIELD: chemistry.
SUBSTANCE: in order to produce a biospecific polymer sorbent for extracting proteinase, an aqueous solution undergoes radical polymerisation, where said solution contains 0.1-1.5 wt % ovomucoid from duck egg albumen, acylated with acyl chloride of acrylic or methacrylic acid, 7.0-20.0 wt % hydrophilic monomer consisting of acrylamide, methacrylamide or N-vinylpyrrolidon, and 0.7-15.0 bifunctional cross-linking agent. The hydrophilic monomer is further mixed with N-ethylbromide dimethylaminoethyl methacrylate, taken in amount of 45-55 wt % with respect to weight of the hydrophilic monomer.
EFFECT: addition of N-ethylbromide dimethylaminoethyl methacrylate to the hydrophilic monomer increases efficiency of sorption of proteinase from biological fluids.
1 tbl, 2 ex
Title | Year | Author | Number |
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METHOD FOR PREPARING BIOSPECIFIC HYDROGEL SORBENT FOR PROTEINASE RECOVERY | 2012 |
|
RU2484475C1 |
BIOSPECIFIC POLYMER ADSORBENT FOR EXTRACTING PROTEINASE (ITS VERSIONS) | 0 |
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METHOD OF THE BIOSPECIFIC ADSORBENT PRODUCING | 1979 |
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METHOD OF HEME-COMPATIBLE POLYMER PRODUCING | 1983 |
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SU1114039A1 |
METHOD OF PURIFYING INHIBITORS OF PROTEINASES | 0 |
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SU964533A1 |
METHOD FOR POLYMER HYDROGEL PRODUCTION, CONTAINING PHYSIOLOGICALLY ACTIVE SUBSTANCES | 2007 |
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RU2342147C1 |
METHOD OF INSULIN DERIVATIVES PREPARING | 1994 |
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Authors
Dates
2011-06-10—Published
2010-02-16—Filed