STRAIN OF HUMAN RHOTAVIRUS FOR PREPARING OF DIAGNOSTIC AND PROPHYLAXIS SERA Russian patent published in 1995 - IPC

Abstract RU 2026345 C1

FIELD: medicine. SUBSTANCE: proposed strain of human rhotavirus - a producer of high-active specific animal serum (for diagnosis) and lactoserum of cows (for prophylaxis of rhotaviral infection). Strain of human rhotavirus 568 is deposited in State Virus Collection of Virology Institute at number GKV 2288. Proposed strain is isolated from sick child with acute gastroenteritis. Strain shows high reproductive activity with development of ЦПД and complete cell destruction after 18-48 h and high immunogenic properties. Strain is stable at laboratory conditions at cultivation at the level of 15 passages. Strain used for immunization of animal (guinea pig, rabbit, cow) can be used for preparing of high-active specific sera. EFFECT: improved method of sera preparing.

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RU 2 026 345 C1

Authors

Vashukova S.S.

Makarova N.G.

Semenov A.V.

Gennad'Eva T.Ja.

Dates

1995-01-09Published

1991-11-26Filed