FIELD: organic chemistry. SUBSTANCE: product: derivatives of pyridine of the formula (I) R1 where R2 and -NR3 - hydrogen, lower alkoxy, halogenated lower alkoxycarbonyl, carboxy or halogen; X - group -O-, -S- or R3 where -O-(CH2)p-OR4, - hydrogen or alkaline metal, lower alkyl or lower alkoxycarbonyl; Z - group R4 where -O(CH2)q-R5, - hydrogen, lower alkyl or benzyl; p - whole number from 1 to 3; group R5 where q - whole number from 1 to 3; -O-(CH2)r-O-(CH2)s-OR6, - halogen, lower alkoxycarbonyl, phenyl or pyridyl; group of the formula R6 where r and s - whole number from 1 to 5; R7 - hydrogen or lower alkyl; group of the formulas (II) OR9, (III) R9, (IV) and (V) where t - whole number from 0 to 2; A - group of the formula (VI) where B - a group of the formula -NH or S; A - lower alkyl, pyridyl or furyl or a group of the formula (VII) where - hydrogen; w - whole number 0 or 1; or Z - group where - hydrogen, lower alkyl or phenyl; n - whole number from 0 to 2; m - whole number from 2 to 10; I and K - hydrogen or lower alkyl. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 4 tbl
Title | Year | Author | Number |
---|---|---|---|
0 |
|
SU1780535A3 | |
DERIVATIVES OF CYCLIC AMIDE OR THEIRS PHARMACOLOGICALLY ACCEPTABLE SALT SHOWING ANTIACETYLCHOLONINE ESTERASE ACTIVITY | 1991 |
|
RU2010794C1 |
BUTENIC OR PROPENIC ACID DERIVATIVES | 1992 |
|
RU2041871C1 |
DIPHENYLMETHYLIMIDAZOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1990 |
|
RU2024521C1 |
TRICYCLE COMPOUNDS OR THEIRS PHARMACEUTICALLY ACCEPTABLE SALTS | 1989 |
|
RU2007406C1 |
DERIVATIVES OF 4,5,6,7-TETRAHYDROBENZIMIDAZOLE | 1991 |
|
RU2033414C1 |
DERIVATIVE OF AMINOBENZOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALT | 1993 |
|
RU2067979C1 |
INDOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND A METHOD OF THEIR SYNTHESIS | 1991 |
|
RU2045518C1 |
METHOD OF SYNTHESIS OF IMIDAZOLE DERIVATIVE | 1990 |
|
RU2026293C1 |
GLYCEROL DERIVATIVES AND A METHOD OF THEIR SYNTHESIS | 1989 |
|
RU2040521C1 |
Authors
Dates
1995-05-20—Published
1992-10-06—Filed