PROCESS FOR PREPARING 3-SUBSTITUTED-2-OXOINDOLES Russian patent published in 1995 - IPC

Abstract RU 2039042 C1

FIELD: medicine as lipoxygenase inhibitor and in biosynthesis of interleinine-1. SUBSTANCE: the process comprises reacting the corresponding heteryl acid with a molar excess of 1,1-carbonyldiimidazole in an inert solvent and in an inert atmosphere and subsequently reacting the resulting product with a 3-substituted-2-oxoindol in the presence of an active agent at 0-50 C in an inert atmosphere and in an inert solvent. EFFECT: improved properties of the title compound. 4 tbl

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RU 2 039 042 C1

Authors

Frederik Dzhakob Ehkhrgott[Us]

Karl Dzhozef Goddard[Us]

Gehri Richard Shul'Te[Us]

Dates

1995-07-09—Published

1991-10-01—Filed