FIELD: organic chemistry. SUBSTANCE: product: new derivatives of 3-substituted 2-hydroxyindoles of the formula (I) H2 where: X, Y - H, Cl, F, Br, 
-alkyl, C1-C6; R - CF3; Q - CONR1R2; 
- H, R1, R2-alkyl; A - C1-C6, 
, F, Cl, Br, J, 
, CN, OR3, S(O)nR4, COOR5, CONR3R5, COR4,; NO2, CH2OR5, OCOR4, SO2NR3R5, NR3R5, N(R3)COR5 - H, R3-alkyl; C1-C6-alkyl; R4=C1-C6 - H, R5-alkyl; n = 0, 1, 2; B - H, F, Cl, Br, C1-C6-alkyl. Synthesized compounds are inhibitors of prostaglandin-CF3, C1-C6-synthase, 5-lipoxygenase and interleukin-1 biosynthesis. EFFECT: improved method of synthesis, enhanced inhibitory effectiveness. 7 cl, 4 tbl
