METHOD OF ISOLATION AND CHEMICAL PURIFICATION OF HYDROXYTETRACYCLINE Russian patent published in 1995 - IPC

FIELD: organic chemistry. SUBSTANCE: method involves isolation of hydrotetracycline base from the mother liquid from which hydroxytetracycline hydrochloride is isolated preliminary. For this mother liquid is added to the ammonium sulfate aqueous solution at mass part from 25 to 40% This ensures to recover to the process about 200 t isopropyl alcohol per year obtained after its regeneration from the mother liquid after technical base precipitation and to prevent disposal of 285 t isopropyl alcohol for refinery. EFFECT: improved method of antibiotic isolation and purification. 2 cl, 1 dwg, 3 tbl