FIELD: organic chemistry. SUBSTANCE: product: substituted phenylamides of 3- (4′-oxo-4′ -H-1′-benzopyranyl-3′) -propene-2-carboxylic acid of the formula (I) where R 1. COCH3. 2. SO2NH2; 3. COOC2H4N(C2H5)2. m. p. is 232-233 C, 273-275 C, 211-213 C, respectively. Compounds of the formula (I) inhibit the reaction of passive skin anaphylaxis by 57.3-76.1% and exceed intal with regard to effectiveness. Synthesized compounds were used in medicine. EFFECT: enhanced effectiveness of synthesized compounds.
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Authors
Dates
1995-07-20—Published
1993-03-01—Filed