FIELD: chemical-pharmaceutical industry; used as compounds having hypotensive, immunostimulating and antiallergic activities. SUBSTANCE: 4-oxo-1.4-dihydropyrimidine hydrochlorides of the general formula: 
or 
. Compound 1: mol. weight 422.5, mp 335-377 C (from acetonitrill), LD50 = 2670 mg/kg. Compound II: mol. weight 320.5, mp 268-270 C, LD50 = 1420 mg/kg. Reagent 1: N-acetyl-2-phenylacetoacetamide. Reagent 2: 4-aminoantipyrine (for compound 1) or 2-aminotysol (for compound II). The process is carried out in icy acetic acid at the boiling point and the resultant product is converted into hydrochloride. The yield of compound 1 61% and the yield of compound II 53%. EFFECT: improved properties of the title product. 5 tbl
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| SUBSTITUTED PHENYLAMIDES OF 3- (4′-OXO- 4′-H- 1′-BENZOPYRANYL-3′) -PROPENE-2-CARBOXYLIC ACID SHOWING ANTIALLERGIC ACTIVITY | 1993 |
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| 1,3-BIS-(ISOBUTYLTHIOETHYL) -5-ISOBUTYLTHIOETHYLHYDROXY -6-METHYLURACIL SHOWING IMMUNOTROPIC ACTIVITY | 1991 |
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