AZETIDINONE DERIVATIVES AND A METHOD OF THEIR SYNTHESIS Russian patent published in 1995 - IPC

Abstract RU 2047602 C1

FIELD: organic chemistry. SUBSTANCE: product: derivatives of azetidinone of the formula (I) where R1 hydroxy-protective group; R2 - C1-C3-alkyl; R3 nonsubstituted pyridyl or pyridyl substituted with C1-C3-alkyl, nonsubstituted quinolyl, phenyl substituted with C1-C3-alkyl or CYNR5-R6,-group where Y oxygen or sulfur, and R5 and R6 are similar or different and mean C1-C6-alkyl or phenyl, or R5 and R6 together form pyrrolidinyl, piperidyl, morpholinyl or azepinyl; R4 hydrogen; Z sulfur or oxygen atom. Reagent 1: compound of the formula (II) where R2, R3 and Z as indicated above; R7,, R8 and R9 are similar or different and mean C1-C4-alkyl or phenyl. Reagent 2: compound of the formula (III) where R1 and R4 as indicated above; R10 - acyloxy-, alkylsulfonyl-, arylsulfonyl-, alkylsulfinyl- or arylsulfinyl-group. Synthesized compounds were used as intermediate products for synthesis carbapenem antibiotics. EFFECT: improved method of synthesis. 5 cl

Similar patents RU2047602C1

Title Year Author Number
FOUR-COORDINATION COMPLEXES OF DIVALENT PLATINUM 1992
  • Jukio Sugimura[Jp]
  • Jukiko Kamejama[Jp]
  • Tosikhiko Khasimoto[Jp]
  • Kimio Ikno Tomojuki Sibata[Jp]
  • Sigeki Muramatsu[Jp]
  • Tomovo Kobajasi[Jp]
RU2039064C1
METHOD OF PRODUCING ANTITUMOR PLATINUM COMPLEXES 1988
  • Jukio Sugimura[Jp]
  • Jukiko Kamejama[Jp]
  • Tosikhiko Khasimoto[Jp]
  • Kimio Iino[Jp]
  • Tomojuki Sibata[Jp]
  • Sigeki Muramatsu[Jp]
  • Tomovo Kobajasi[Jp]
RU2007413C1
CARBOPENEM DERIVATIVES AND A METHOD OF THEIR SYNTHESIS 1993
  • Isao Kavamoto[Jp]
  • Rokiro Ehndo[Jp]
  • Masao Mijauti[Jp]
  • Katsuja Isikava[Jp]
  • Katsukhiko Vatanabe[Jp]
  • Khirosi Jasuda[Jp]
  • Satosi Okhija[Jp]
  • Jukio Utsui[Jp]
RU2097383C1
FUNGICIDAL OXETANE DERIVATIVES AND SALTS THEREOF 1992
  • Khideo Takesiba[Jp]
  • Dzunzo Tobitsuka[Jp]
  • Kazuo Sato[Jp]
  • Khisaki Kadzino[Jp]
  • Khirojuki Itokh[Jp]
  • Jukiesi Takakhi[Jp]
  • Khirosi Okhta[Jp]
  • Sadao Onda[Jp]
  • Noriko Takeda[Jp]
  • Tosijuki Konosu[Jp]
  • Khirosi Jasuda[Jp]
RU2044736C1
HEXAHYDRONAPHTHALENE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITION 1993
  • Khirosi Kogen[Jp]
  • Sadao Isikhara[Jp]
  • Tejitiro Koga[Jp]
  • Ejiti Kitazava[Jp]
  • Nobufuza Serizava[Jp]
  • Kiesi Khamano[Jp]
RU2104997C1
α, ω-DIARYL ALKANES AND METHOD FOR THEIR PRODUCTION 1993
  • Kojti Fudzimoto[Jp]
  • Naoki Tanaka[Jp]
  • Fumitosi Asaj[Jp]
  • Tomijosi Ito[Jp]
  • Khirojuki Kojke[Jp]
RU2105752C1
AZASTEROIDAL COMPOUNDS 1991
  • Koiti Kodzima[Jp]
  • Khitosi Kurata[Jp]
  • Khiroesi Khorikosi[Jp]
  • Takakazu Khamada[Jp]
RU2070204C1
SILICON-CONTAINING COMPOUNDS OR THEIR SALTS SHOWING FUNGICIDE ACTIVITY AND METHOD OF THEIR SYNTHESIS 1992
  • Dzuntso Tobitsuka[Jp]
  • Khideo Takesiba[Jp]
  • Jasukhiko Kondo[Jp]
  • Khirosi Okhta[Jp]
  • Sigekhiro Kato[Jp]
RU2069213C1
CRYSTALLINE PIVALOYLHYDROXYMETHYL-(1R, 5S, 6S)-[(4R)-2-OXO-4--PYRROLIDINYLTHIO]-6-[(1R)-1-HYDROXYETHYL]-1-METHYL-1-CARBAPE--NE-2-EME-3-CARBOXYLATE AND METHOD OF ITS SYNTHESIS 1993
  • Isao Kavamoto[Jp]
  • Masao Mijauti[Jp]
  • Rokuro Ehndo[Jp]
RU2090567C1
METHOD OF PRODUCING DERIVATIVES OF PERHYDROTHIAZEPIN OR ACID-ADDITIVE PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF 0
  • Khiroaki Yanagisava
  • Sadao Isikhara
  • Akiko Ando
  • Takuro Kanazaki
  • Khiroyuki Koike
  • Esio Tsudzita
SU1435151A3

RU 2 047 602 C1

Authors

Koiti Khirai[Jp]

Judzi Ivano[Jp]

Khiroo Kojama[Jp]

Takakhide Nisi[Jp]

Akira Esida[Jp]

Kozo Oda[Jp]

Dates

1995-11-10Published

1992-05-29Filed