AZASTEROIDAL COMPOUNDS Russian patent published in 1996 - IPC

FIELD: medicine. SUBSTANCE: product: azasteroidal compounds of general formula I wherein is H, unsubstituted R¹ alkyl, benzyl; C₁-C₄ is R²-C₁-C₄-alkyl substituted by phenyl, furyl or thienyl group; R³ is H, unsubstituted C₁-C₄-alkyl, C₁-C₄-alkyl substituted by hydroxy or carboxy group or R³ is C₃-C₆ alkenyl, A-B and C-D are carbon-carbon single or double bonds; said phenyl groups may be substituted by at least by one substituent such as C₁-C₆-alkyl, C₁-C₄-alkoxy, C₂-C₄- alkoxycarbonyl, hydroxy-, halogen, acetoamido group. 62 individual compounds are claimed in claim 2. Compounds I are capable of inhibiting 5-α-reductase. EFFECT: improved properties of the azasteroidal compounds. 4 tbl