α, ω-DIARYL ALKANES AND METHOD FOR THEIR PRODUCTION Russian patent published in 1998 - IPC

FIELD: medicine, as antagonist of receptor of serotonine-2. SUBSTANCE: diaryl alkanes have formula I where R¹ is aryl, R² is H, R³ is -BNR⁴R⁵, group where R⁴ and R⁵ is H, alkyl, or R⁴ and R⁵ together with nitrogen atom which with they are bound represent heterocyclic group comprising 3-6 ring atom and B is alkylene C₂-C₆ group or -D-R⁷ group where D is single carbon-carbon bond or alkylene group, A is C₂-C₈ alkylene group. Compound having formula II is used as reagent 1. Compound having formula Z-B-NR⁴R⁵ where Z is OH group or group enables splitting, B, R⁴ and R⁵ are as it mentioned above is used as reagent 2. Compound or its pharmaceutically acceptable salts may be used in medicine. EFFECT: improved quality.