Show metadata Hide metadata

(19)

(11)

2 047 620

(13)

(51)

IPC

(21) (22)

Application

4899418/04, 1990-11-29

(22)

Actual filing date

1990-11-29

(45)

Published

1995-11-10

(72)

Inventor

Pekel' N.D.Seredenko V.I.Rudakova I.P.Mikhajlov A.M.Smirnova E.G.Lutsenko V.V.Artjushkina A.G.Pavlova A.B.

(73)

Holder

Nauchno-Proizvodstvennoe Ob"Edinenie

METHOD OF FLAVINE-ADENINE DINUCLEOTIDE PURIFICATION Russian patent published in 1995 - IPC

Abstract RU 2047620 C1

FIELD: medicine. SUBSTANCE: product: flavine-adenine dinucleotide (FAD). The yield is 77.2% content of basic substance is 99.5% Reagent 1: FAD. Reagent 2: diethylaminoethyl-spherone in Cl^--form, ionic strength is 0.05-0.5 M and pH 3-5, and "Polysorb C". Reaction conditions: aqueous solution of FAD is passed through the column with adsorbents. Impurities were desorbed with buffer containing NaCl and CH₃CO₂Na, FAD is desorbed with NaCl at ionic strength 0.1-0.5 M, eluate is desalted and concentrated by 10-20-fold on the "Polysorb C". Crystalline FAD is isolated by precipitation with ethanol. FAD is used as pharmaceutical preparation for treatment patients with glaucoma, psoriasis, seborrhea, hereditary hemolytic anemia. EFFECT: improved method of purification. 1 tbl

Similar patents RU2047620C1

Title	Year	Author	Number
METHOD FOR PURIFICATION OF RECOMBINATE PROTEIN WHICH CONTAINS PROINSULIN SEQUENCE	1990	Leonova E.B. Gavrjuchenkova L.P. Gromova O.A. Khrushcheva T.A. Tsukanova L.N. Korshunov M.A. Mikhlin V.S. Melekhov V.M. Beljaev S.V. Vul'Fson A.N. Mal'Tsev K.V. Kulikov S.V. Morozov S.M.	SU1839446A1
PROCESS FOR PREPARING S-SULFONATE	1991	Leonova E.B. Gavrjuchenkova L.P. Gromova O.A. Khrushcheva T.A. Tsukanova L.N. Korshunov M.A. Mikhlin V.S. Melekhov V.M. Beljaev S.V. Vul'Fson A.N. Mal'Tsev K.V. Kulikov S.V.	RU2025474C1
METHOD OF PREPARATION OF RECOMBINANT ANTAGONIST OF HUMAN INTERLEUKINE-1 RECEPTOR "ARIL"	2004	Antipova Tat'Jana Olegovna Antropova Galina Fedorovna Ishchenko Aleksandr Mitrofanovich Ketlinskij Sergej Aleksandrovich Mitrofanov Evgenij Vital'Evich Pigareva Natalija Vasil'Evna Poljakova Elena Akimovna Protasov Evgenij Aleksandrovich Sventitskij Evgenij Nikolaevich Simbirtsev Andrej Semenovich Solov'Eva Ljudmila Jakovlevna Frolov Vladimir Nikolaevich Shalaeva Ol'Ga Nikolaevna	RU2326947C2
METHOD FOR ISOLATION OF RECOMBINANT PROINSULIN	1991	Leonova E.B. Gavrjuchenkova L.P. Gromova O.A. Khrushcheva T.A. Tsukanova L.N. Korshunov M.A. Melekhov V.M. Mikhlin V.S. Beljaev S.V. Vul'Fson A.N. Mal'Tsev K.V. Kulikov S.V.	RU2049793C1
CELLULOSE DIETHYLAMINOETHYL ETHER AS SORBENT FOR RECOVERY AND PURIFICATION OF ENZYME PREPARATIONS AND PROCESS FOR PURIFICATION OF STREPTOKINAZE	1993	Boldyrev Aleksandr Georgievich Zajtsev Petr Ivanovich Stepanov Valerij Vladimirovich Moloshnikov Vladimir Alekseevich Fedorova Natal'Ja Mikhajlovna Kaloshin Valentin Genrikhovich Parr Galina Semenovna Borisova Valentina Alekseevna Andreeva Teodora Vasil'Evna	RU2076870C1
METHOD OF COLLAGENASE PREPARATION PRODUCING	1991	Isaev V.A. Rudenskaja G.N. Kupenko O.G. Stepanov V.M. Popova I.M. Didenko Ju.G.	RU2008353C1
METHOD OF PRODUCING ADENOVIRAL ANTIGENS	0	Khilko Sergej Nikolaevich Ponomareva Tatyana Ivanovna Grigorev Vitalij Gennadevich Komarov Yurij Sergeevich Karpova Olga Viktorovna Tikhonenko Tomas Iosifovich	SU1364342A1
METHOD OF INSULIN PREPARING	1992	Katrukha S.P. Debabov V.G.	RU2027444C1
METHOD FOR CHROMATOGRAPHIC EXTRACTION AND PURIFICATION OF IMMUNOGLOBULINS	2018	Sarvin Nikita Andreevich Karasev Viktor Semenovich Bochkova Olga Petrovna Staroverov Sergej Mikhajlovich	RU2694620C1
METHOD OF RIBONUCLEASE ISOLATION	0	Ezhov Vladimir Aleksandrovich Prikhodko Anna Grigorevna Lishevskaya Marina Osipovna Morin Boris Pavlovich	SU734261A1

RU 2 047 620 C1

Authors

Pekel' N.D.

Seredenko V.I.

Rudakova I.P.

Mikhajlov A.M.

Smirnova E.G.

Lutsenko V.V.

Artjushkina A.G.

Pavlova A.B.

Dates

1995-11-10—Published

1990-11-29—Filed