FIELD: biotechnology, bioactive compounds. SUBSTANCE: chitosan is treated with complex of chlorosulfonic acid and oleum with amide in amide solvent or dimethylsulfoxide in the presence of sodium or potassium nitrite. Molar ratio of nitrite and chitosan is 1:(0.001-1), temperature is from room to 50 C, time is 60 min, not above. Product is used for preparing bioactive compounds showing anticoagulating, antisclerotic and antiviral actions and shows increased capability for specific binding low density lipoproteins from the blood. EFFECT: improved method of sulfated chotosan preparing. 1 tbl
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