FIELD: medicinal biotechnology. SUBSTANCE: method involves preparing the strain of hybrid cultured murine cells which produces monoclonal antibodies to thyroxine. Strain is prepared by hybridization of murine splenocytes of line BALB/c with myeloma X63.Ag 865.3 cells. Monoclonal antibodies show affinity constant 3·109M-1, their crossed reactivity with triiodothyronine is 1% EFFECT: improved method of hybrid cells preparing. 2 dwg
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