METHOD OF ANTITOXIC SERUM PREPARING Russian patent published in 1996 - IPC

FIELD: medicinal industry. SUBSTANCE: hyperimmune equine plasma is treated with rivanol, pepsin and 10% aluminium hydroxide followed by purification and concentration on ultrafiltering diaphragm at retention threshold of substance 100 kD by molecular mass. Additional purification from small-dispersed impurities is carried out by microfiltration on diaphragm at pore size 0.2 mcm. Yield of the end product is 55-80%. Preparation shows chromatographically homogeneity. EFFECT: increased yield and purity, simplified technological process. 1 dwg, 2 tbl