FIELD: medicine. SUBSTANCE: product: octane oxaspiro [2,5] derivative of formula I wherein R1 is carbamoyl, lower alkyl carbamoyl, hydroxy (lower) alkyl carbamoyl, lower alkoxy (lower) alkyl carbamoyl; R2 is lower alkoxy; R3 oxirane R6 is lower alkoxycarbonyl; R7 is lower alkoxycarbonyl (lower) alkyl or phenyl or naphthyl (lower) alkyl; R8 is lower alkanoyl or lower alkylcarbamoyl or pharmaceutically acceptable salt of this compound. Reagent 1: hydroxy phenyl oxirane. Reagent 2: R1X. EFFECT: improved properties of the title compound. 8 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF DISEASE TREATMENT INTERMEDIARY AGENT OF THAT IS TACHIKININ | 1991 |
|
RU2073683C1 |
| PEPTIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF PROPHYLAXIS AND ELIMINATION OF THROMBOSIS | 1992 |
|
RU2103276C1 |
| DERIVATIVES OF PYRAZOLO-[1,5-A]-PYRIDINE OR THEIR PHARMACEUTICAL ACCEPTABLE SALTS AND METHOD OF THEIR SYNTHESIS | 1992 |
|
RU2069662C1 |
| TRICYCLE COMPOUNDS OR THEIRS PHARMACEUTICALLY ACCEPTABLE SALTS | 1989 |
|
RU2007406C1 |
| INDOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND A METHOD OF THEIR SYNTHESIS | 1991 |
|
RU2045518C1 |
| PEPTIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1992 |
|
RU2043365C1 |
| METHOD OF PRODUCING PYRAZOLE-PURIDINE DERIVATIVE OR ITS SALT | 1990 |
|
RU2007403C1 |
| METHOD OF SYNTHESIS OF CEPHEM COMPOUNDS OR THEIR ACID-ADDITIVE SALTS | 1988 |
|
RU2017744C1 |
| DERIVATIVES OF INDOLYLPYPERIDINE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1991 |
|
RU2039056C1 |
| ANTIBIOTIC COMPOSITION | 1988 |
|
RU2029549C1 |
