LIPID ANALOGS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 1997 - IPC

Abstract RU 2076107 C1

FIELD: organic chemistry. SUBSTANCE: product: lipid analogs of the general formula (I): where: R1 - OH, ; R2 - where: R6 and R7 - H, F; R8 - H, OH or tetradecanoyloxy; - tetradecanoyl or R9 where: R10 - H, F; R4 - H, OH, tetradecanoyloxy or 2,2-difluorotetradecanoyloxy; - OH, R< and at least one of groups R4 and - group R5; R2 - OH, F at condition that exception of case when at least one of R3 and R2 - tetradecanoyl substituted with F or at least one substituent of the group: F, OH, tetradecanoyloxy, or at least one of R3 and R4 - tetradecanoyl substituted with at least one fluoro-substituted tetradecanoyloxy-group, or their pharmaceutically acceptable salts. Synthesized compounds were used as immunoregulating and immunostimulating preparations. EFFECT: improved method of synthesis. 6 cl, 4 tbl

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RU 2 076 107 C1

Authors

Masao Siozaki[Jp]

Noboru Isida[Jp]

Tomovo Kobajasi[Jp]

Tetsuo Khiraoka[Jp]

Masami Arai[Jp]

Juzuru Akamatsu[Jp]

Masakhiro Nisidzima[Jp]

Dates

1997-03-27Published

1992-09-09Filed