METHOD OF PREPARING THE AGENT FOR INDIRECT LYMPHOSCINTIGRAPHY Russian patent published in 1997 - IPC

FIELD: radioisotopic diagnosis, pharmacy. SUBSTANCE: method involves preparing the colloidal solution of rhenium sulfide labeled with To-98m (KOPEH) and its binding with human serum albumin and saline solution up to the final albumin concentration 3.0-3.5% and volume activity 34-42 MBk in 1 ml. Binding the known preparation (KOPEH) with human serum albumin ensures to obtain preparation exhibiting the stable colloidal-opsonine links with carrier - human albumin molecules. The proposed preparation is released from "tissue depot" at the increased velocity as compared with that of the known one. Preparation shows the constant accumulation rate in lymphonodules. EFFECT: improved quality, enhanced lymphotropic property, decreased radiation loading.