FIELD: organic chemistry. SUBSTANCE: product: 3'-(2-amino-1-hydroxyethyl)-4'-fluoromethanesulfoneamide or its optically active isomers, pharmacological salts, m. p. is 176-179 C, empirical formula is C9H13FN2O3. Reagent 1: 3'-(2-aminoacetyl)-4'-fluoromethanesulfone anilide. Reagent 2: sodium borohydride. Reaction condition: in methanol medium, at heating. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 2 cl, 5 tbl
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Authors
Dates
1997-03-27—Published
1991-02-06—Filed