IMIDAZOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE ESTERS AND A METHOD OF THEIR SYNTHESIS Russian patent published in 1997 - IPC

Abstract RU 2086541 C1

FIELD: organic chemistry. SUBSTANCE: product: compound of the formula (I) where: R1 - hydrogen, alkyl, cycloalkyl or alkanoyl; R2 - single bond, alkylene or alkylidene; R3 and R4 - each means hydrogen or alkyl; R6 - carboxyl or tetrazole-5-yl; X - oxygen or sulfur, and their pharmaceutically acceptable salts and esters that are antagonists of angiotensin-II and can be used for treatment and prophylaxis of hypertension and cardiovascular diseases. EFFECT: improved method of synthesis, enhanced effectiveness of treatment and prophylaxis. 21 cl, 2 tbl

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RU 2 086 541 C1

Authors

Khiroaki Janagisava[Jp]

Jasuo Simodzi[Jp]

Esija Amemija[Jp]

Takuro Kanazaki[Jp]

Khirojuki Koike[Jp]

Tosio Sada[Jp]

Dates

1997-08-10Published

1993-06-01Filed