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2 077 590

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IPC

(21) (22)

Application

94017639/13, 1994-05-20

(22)

Actual filing date

1994-05-20

(45)

Published

1997-04-20

(72)

Inventor

Donova M.V.Dovbnja D.V.Kalinichenko A.N.Arinbasarova A.Ju.Vagabova L.M.Morozova Z.V.Koshcheenko K.A.

(73)

Holder

Institut Biokhimii I Fiziologii Mikroorganizmov Ran

METHOD OF 9-ALPHA-HYDROXYANDROST-4-ENE-3,17-DIONE PREPARING Russian patent published in 1997 - IPC

Abstract RU 2077590 C1

FIELD: biotechnology. SUBSTANCE: product: 9-alpha-hydroxyandrost-4-ene-3,17-dione is prepared by sterol transformation, for example, sitosterol, cholesterol and others, with bacteria of genus Mycobacterium in the presence of water-soluble chemical derivatives of beta-cyclodextrin, for example, alkylene glycol (ethylene glycol-, propylene glycol-) or carboxyalkyl (carboxymethyl-)-beta-cyclodextrin. Method ensures to enhance the yield of the end product at high substrate loading (5-20 g/l) and effectiveness of process. EFFECT: increased yield, simplified process.

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RU 2 077 590 C1

Authors

Donova M.V.

Dovbnja D.V.

Kalinichenko A.N.

Arinbasarova A.Ju.

Vagabova L.M.

Morozova Z.V.

Koshcheenko K.A.

Dates

1997-04-20—Published

1994-05-20—Filed