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2 041 951

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C1

(51)

IPC

(21) (22)

Application

5065537/13, 1992-10-09

(22)

Actual filing date

1992-10-09

(45)

Published

1995-08-20

(72)

Inventor

Redikul'Tsev Ju.V.Sukhodol'Skaja G.V.Koshcheenko K.A.Kudrjashov V.K.

(73)

Holder

Institut Biokhimii I Fiziologii Mikroorganizmov Ran

METHOD FOR PRODUCTION OF PREDNISOLONE Russian patent published in 1995 - IPC

Abstract RU 2041951 C1

FIELD: biotechnology. SUBSTANCE: suspension of hydrocortison in phosphate buffer is prepared. Then its transformation by immobilized cells of Arthrobacter globifornis is carried out. Then suspension which contains product is separated and heated at 80-95 C till crystals of product are dissolved. Thus prepared solution is cooled and crystals are isolated of liquid phase. Said liquid phase is then used for preparing suspension of hydrocortison as buffer solution. EFFECT: improves efficiency of the method. 1 dwg

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RU 2 041 951 C1

Authors

Redikul'Tsev Ju.V.

Sukhodol'Skaja G.V.

Koshcheenko K.A.

Kudrjashov V.K.

Dates

1995-08-20—Published

1992-10-09—Filed

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