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2 080 877

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C1

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IPC

(21) (22)

Application

94012997/14, 1994-04-12

(22)

Actual filing date

1994-04-12

(45)

Published

1997-06-10

(72)

Inventor

Kulagin V.F.Nigmatullin T.G.Zagidullin N.V.Ishkil'Dina L.A.

(73)

Holder

Nauchno-Proizvodstvennoe Ob"Edinenie

METHOD OF INACTIVATION OF VIRAL CONTAMINATION IN HUMAN LEUKOCYTE INTERFERON PREPARATION Russian patent published in 1997 - IPC

Abstract RU 2080877 C1

FIELD: medicinal industry. SUBSTANCE: sealed ampoules containing dry interferon preparation were placed in casettes and subjected for two-fold irradiation on gamma-unit RDS-60 at total dose 15-25 kGr. This treatment provides the complete inactivation of any possible contaminating viruses and, therefore, the complete safety with respect to lymphotropic viruses. Antiviral activity of interferon is retained after treatment. The treated interferon exhibits safety, sterility, absence of toxicity. EFFECT: improved method of inactivation.

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RU 2 080 877 C1

Authors

Kulagin V.F.

Nigmatullin T.G.

Zagidullin N.V.

Ishkil'Dina L.A.

Dates

1997-06-10—Published

1994-04-12—Filed

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