FIELD: medicinal industry. SUBSTANCE: virus gel-filtrate is treated with trypsin at concentration 0.5-1.0% that cleavages selectively inert proteins (ovalbumin and nonovalbumin antigens) converting their to the fraction of low-molecular compounds. Level of allantois impurities in vaccine preparation is decreased by 4-16-fold. EFFECT: improved method of preparing and quality of vaccine. 4 tbl
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Authors
Dates
1997-06-27—Published
1993-05-12—Filed