FIELD: natural organic compounds. SUBSTANCE: invention describes derivatives of galanthamine of the formula (I) 
where R1,R2,R3 and R4 have values determined above. Synthesized compounds are inhibitors of acetylcholine esterase and can be used for treatment of patients with memory impairment exhibiting decreased cholinergic function, and pharmaceutical compositions containing the indicated compounds. EFFECT: improved method of synthesis, enhanced effectiveness. 8 cl, 2 tbl
| Title |
Year |
Author |
Number |
| GALANTAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION |
1994 |
- Rajmond V.Koslej
- Larri Dehvis[Us]
- Veronika Taberna[Uy]
|
RU2109743C1 |
| GALANTHAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION |
1994 |
- Rajmond V.Koslej
- Larri Dehvis
- Veronika Taberna
|
RU2113438C1 |
| SUBSTITUTED BENZOTHIENYLPIPERAZINES, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1996 |
- Nikolas Dzh.Rib
- Dzhon G.Jurchak
- Abdul E.Mertlib
|
RU2157371C2 |
| CARBAMIC ACID DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE ACID-ADDITIVE SALTS, METHOD OF THEIR SYNTHESIS (VARIANTS) AND PHARMACEUTICAL COMPOSITION |
1992 |
- Dehniz Mehri Flehnagan[Us]
- Lorehns Leo Martin[Us]
|
RU2103271C1 |
| METHOD FOR STEREOSELECTIVE SYNTHESIS OF ALKYLATED HYDROXYINDOLES AND METHOD FOR PREPARING OPTICALLY PURE ALKYLATED HYDROXYINDOLE ENANTIOMER |
1994 |
- Tomas Bing Kin Lii[Us]
- Dzhordzh Seung-Kit Vong[Us]
|
RU2109013C1 |
| [(ARYLALKYLPIPERIDINYL-4-YL)-METHYL]-2A,3,4,5-TETRAHYDRO-1-ONES OR THEIR ACID-ADDITIVE SALTS AND A METHOD OF THEIR PREPARING |
1992 |
- Rehjmond V.Kosli Ml.[Us]
- Bettina Shpal'[Us]
|
RU2043989C1 |
| USE OF N-(PYRIDINYL)-1H-INDOL-1-AMINES FOR SYNTHESIS OF MEDICATION USED FOR TREATMENT OF PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDERS |
1994 |
- Satapana Kongzameht
- Krejg Pol Smit
- Ehnn Tereza Vudz
|
RU2164795C2 |
| 1-[PYRIDO(3,4-B)-1,4-OXAZINYL-4-YL]-1H-INDOLES, METHOD OF THEIR SYNTHESIS, COMPOSITION ON THEIR BASIS AND DERIVATIVE OF N-(4-PYRIDINYL)-1H-INDOLE-1-AMINE |
1992 |
- Richard Charl'Z Ehffland[Us]
|
RU2042680C1 |
| DERIVATIVES OF N-(ARYLOXYALKYL)-HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1990 |
- Dzhozef Tomas Strupchevski
- Grover Kleveland Khelslej
- Julin Chiang
- Kennet Dzh. Bordeo
|
RU2147583C1 |
| BENZISOTHIAZOLE- OR BENZISOXAZOLE-3-CARBOXAMIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIPSYCHOTIC ACTIVITY |
1992 |
- Nikolas Dzh.Khrib[Us]
- Dzhon G.Dzhurkak[Us]
|
RU2039057C1 |
