FIELD: organic chemistry. SUBSTANCE: invention relates to method of enantioselective synthesis of phenylisoserine derivatives of the general formula (I) where: R means phenyl or tert.-butoxy; R′ means protective group for alcoholic function. Compounds of the general formula (I) can be used for synthesis of taxane derivatives that show antitumor and antileukemic activity. EFFECT: improved method of synthesis.
Title |
Year |
Author |
Number |
METHOD OF STEREOSELECTIVE PREPARATION OF SYN- PHENYL- ISOSERINE DERIVATIVES |
1991 |
- Arlen Korrea[Br]
- Zhan-Noel' Deni[Be]
- Ehndrju Ehlliot Grin[Us]
|
RU2091368C1 |
DERIVATIVE OF $$$-PHENYLISOSERINE, METHOD OF ITS STEREOSELECTIVE SYNTHESIS, THE PARENT COMPOUND FOR ITS SYNTHESIS, METHOD OF SYNTHESIS OF TAXANE AND INTERMEDIATE PRODUCTS |
1993 |
- Zhan-Noel' Deni[Be]
- Andrev Grin[Us]
- Alis Kanazava[Br]
|
RU2109010C1 |
METHOD OF PREPARING 1,3-OXAZOLIDINE-5- CARBOXYLIC ACIDS (VARIANTS) |
1993 |
- Zhan-Noel' Deni
- Ehndrju Grin
- Alis Kanazava
|
RU2114834C1 |
METHOD OF SYNTHESIS OF TAXANE DERIVATIVES AND INTERMEDIATE COMPOUNDS OF SYNTHESIS |
1993 |
- Zhan-Noel' Deni
- Ehndrju Grin
- Alis Kanazava
|
RU2118958C1 |
METHOD FOR PRODUCTION OF β-PHENYL ISOSERINE AND ITS ANALOGES, DERIVATIVES OF β-PHENYLISOSERINE, DERIVATIVES OF AZETIDINONE |
1993 |
- Zhan-Dominik Burza[Fr]
- Alen Kommerson[Fr]
|
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DERIVATIVES OF TAXANE |
1993 |
- Deni Zhan-Noel'
- Grin Ehndrju
- Kanazava Alis
|
RU2188198C2 |
METHOD FOR PRODUCTION OF TAXANE DERIVATIVES AND INTERMEDIATES BY THEIR PRODUCTION |
1993 |
- Alen Kommerson
- Ehrik Did'E
- Ehli Fuke
|
RU2116302C1 |
PERHYDROISOINDOLE DERIVATIVES AND METHOD OF PREPARATION THEREOF |
1993 |
- Daniel' Ashar
- Serzh Grizoni
- Zhan-Ljuk Malleron
- Zhan-Fransua Pejronel'
- Mishel' Tabart
|
RU2120438C1 |
TAXOIDS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS AND PHARMACEUTICAL COMPOSITION |
1993 |
- Ehrve Bushar
- Zhan-Dominik Burza
- Alen Kommerson
|
RU2139864C1 |
N-BENZYL-β-PHENYLISOSERIN-(2R,3S), METHOD FOR ITS PRODUCTION AND METHOD OF PRODUCTION OF ESTER OF b-PHENYLISOSERIN-(2R,3S) |
1991 |
- Zhan-P'Er Djushesn[Fr]
- Mishel' Mjul'Ozer[Fr]
|
RU2074172C1 |