FIELD: biotechnology, molecular biology. SUBSTANCE: method involves insertion of the human cloned erythropoietin gene in plasmid pSVdEpoL Mo in cells of Chinese hamster transplanted ovary strain CHO tk and the strain VSKK(P)637-D is obtained. Strain CHO Epo-2 shows high (1500-1800 U/ml) and stable under nonselective conditions production of human erythropoietin. EFFECT: high yield of erythropoietin. 7 dwg
Title |
Year |
Author |
Number |
STRAIN OF CULTIVATED CELLS OF CHINA HAMSTER - PRODUCER OF ERYTHROPOETYN OF MAN |
0 |
- Zelenin Mikhail Gavrilovich
- Kramerova Irina Aleksandrovna
- Kolobkov Sergej Leonidovich
- Filyakina Natalya Saidovna
- Egorov Boris Borisovich
|
SU1555359A1 |
RECOMBINANT PLASMID DNA PKEP-9 ENCODING HUMAN ERYTHROPOIETIN, STRAIN OF CULTURED CHINESE HAMSTER OVARY CELLS CHOPE-9 - A PRODUCER OF HUMAN ERYTHROPOIETIN |
1997 |
- Urmanova M.A.
- Shchelkunov S.N.
- Pozdnjakov S.G.
- Kolokol'Tsova T.D.
- Jurchenko N.D.
- Nesterov A.E.
- Shumakova O.V.
- Kostina N.E.
- Nechaeva E.A.
|
RU2118662C1 |
PLASMID FOR EXPRESSION IN CELL OF CHINESE HAMSTER, CELL OF CHINESE HAMSTER - PROTEIN PRODUCER WITH Gla-DOMAIN, AND METHOD FOR OBTAINING PROTEIN WITH Gla-DOMAIN |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2535871C1 |
EUKARYOTIC HOST CELL FOR EXPRESSION OF DARBEPOETIN, EXPRESSION VECTOR AND METHOD OF PRODUCTION OF DARBEPOETIN ALFA |
2013 |
- Seregin Jurij Aleksandrovich
- Shukurov Rakhim Rakhmankulyevich
- Krjazhevskikh Irina Sergeevna
- Khamitov Ravil' Avgatovich
- Sautkina Elena Nikolaevna
- Orlova Natal'Ja Vladimirovna
|
RU2523948C1 |
EXPRESSION PLASMID VECTOR FOR HETEROLOGICAL EXPRESSION OF RECOMBINANT PROTEINS, HIGH-FREQUENCY INTEGRATION AND AMPLIFIED AMPLIFICATION OF EXPRESSION CASSETTE IN CELLS OF MAMMALS, BICISTRONIC MESSENGER RIZIFORM, METHOD OF PRODUCTION OF STABLE LINES OF PRODUCENTS OF RECOMBINANT PROTEINS USING SPECIFIED VECTOR, METHOD FOR PRODUCTION OF RECOMBINANT PROTEINS |
2011 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2488633C1 |
PLASMID FOR EXPRESSION OF HUMAN RECOMBINANT BLOOD CLOTTING FACTOR IX, CHO CELL PRODUCING HUMAN RECOMBINANT BLOOD CLOTTING FACTOR IX AND METHOD OF PRODUCING SAID FACTOR |
2014 |
- Kovnir Sergej Vladimirovich
- Orlova Nadezhda Aleksandrovna
- Vorobev Ivan Ivanovich
- Khodak Yuliya Vladimirovna
- Dronina Mariya Alekseevna
- Smirnov Ivan Vitalevich
- Ponomarenko Natalya Aleksandrovna
- Skryabin Konstantin Georgievich
- Gabibov Aleksandr Gabibovich
|
RU2585532C2 |
EXPRESSION PLASMID DNA pCID-PROC CODING HUMAN PROTEIN C AND CELL LINE DG-CID-PROC-1 PRODUCING RECOMBINANT HUMAN PROTEIN C |
2008 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2469093C2 |
EXPRESSION PLASMID VECTOR OF MONOCISTRONIC EXPRESSION OF RECOMBINANT PROTEINS IN MAMMALIAN CELLS, CELL LINE OF MAMMALS-PRODUCERS OF RECOMBINANT PROTEIN, METHOD OF OBTAINING RECOMBINANT PROTEIN |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2552170C2 |
EXPRESSION PLASMID FOR HUMAN RECOMBINANT COAGULATION FACTOR VIII WITH DELETED B-DOMAIN IN CHO CELLS, CHO CELL PRODUCING HUMAN RECOMBINANT COAGULATION FACTOR VIII WITH DELETED B-DOMAIN, AND METHOD FOR PRODUCING ABOVE FACTOR |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
- Vorob'Ev Andrej Ivanovich
|
RU2561466C2 |
RECOMBINANT PLASMID DNA OF pBiPr-ABIgA2m1F16-ht TO OBTAIN RECOMBINANT IMMUNOGLOBULIN A OF ISOTYPE IgA2m1 |
2016 |
- Aliev Tejmur Kantamirovich
- Argentova Viktoriya Vitalevna
- Bokov Maksim Nikolaevich
- Votchitseva Yuliya Aleksandrovna
- Dementeva Irina Grigorevna
- Dolgikh Dmitrij Aleksandrovich
- Kirpichnikov Mikhail Petrovich
- Pozdnyakova Lyubov Petrovna
- Sveshnikov Petr Georgievich
- Toporova Viktoriya Aleksandrovna
|
RU2671477C2 |