FIELD: pharmaceutical industry. SUBSTANCE: method involves purification of the preparation an aqueous solution with dichloroethane, extraction of the end product with n-butanol and washing with water. Processes were combined by time and carried out continuously and successively in countercurrent at intensive mechanical stirring. The end product is extracted with n-butanol after treatment of the preparation an aqueous solution with dichloroethane directly. EFFECT: decreased time of process, increased yield of the end product, decreased consumption of raw and solvents. 1 dwg
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Authors
Dates
1997-09-20—Published
1994-08-08—Filed