FIELD: biotechnology, virology. SUBSTANCE: biological material is subjected for purification by its passing through filter or filter system inoculated preliminary with virus Leviviridae family. Virus titer as an index of virus removing degree is determined before and after filtration. Method ensures to control virus removing and/or pathogenic material during the purification process. EFFECT: improved method of purification. 10 cl, 2 dwg, 4 tbl
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