FIELD: medicine.
SUBSTANCE: invention represents an agent for neutralising smallpox virus representing an artificial single-chain human 1A antibody having an amino acid sequence presented in the claim material, and exposed on a surface of the filamentous phage M13.
EFFECT: invention enables neutralising smallpox virus.
7 dwg, 4 ex
Title | Year | Author | Number |
---|---|---|---|
COMBINATORIAL FRAGMID LIBRARY OF HUMAN SINGLE-STRANDED ANTIBODIES ENRICHED WITH ANTIBODIES AGAINST VARIOLOVACCINE VIRUS, RECOMBINANT FRAGMID pHEN-2A8 DNA CONTAINING UNIQUE GENE OF HUMAN SINGLE-STRANDED ANTIBODY, CAPABLE OF NEUTRALIZING VARIOLOVACCINE VIRUS AND COWPOX VIRUS, AND ARTIFICIAL HUMAN SINGLE-STRANDED 2A8 ANTIBODY CAPABLE OF NEUTRALIZING VARIOLOVACCINE VIRUS AND COWPOX VIRUS | 2005 |
|
RU2311927C2 |
RECOMBINANT FRAGMID DNA pHEN-TAB CONTAINING HUMAN SINGLE-STRAND ANTIBODY GENE, CAPABLE OF BINDING OF HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT Escherichia coli BACTERIA STRAIN AS PRODUCER OF HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT SOLUBLE HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA | 2005 |
|
RU2307163C2 |
RECOMBINANT PLASMID DNA pQE-p35d PROVIDING SYNTHESIS OF p35d RECOMBINANT PROTEIN OF COWPOX VIRUS, Escherichia coli BACTERIAL STRAIN THAT IS PRODUCER OF p35d RECOMBINANT PROTEIN OF COWPOX VIRUS, AND p35d RECOMBINANT PROTEIN OF COWPOX VIRUS USED TO ENGINEER TEST SYSTEMS AND TO PREPARE ORTHOPOXVIRUS SPLIT VACCINES | 2012 |
|
RU2511037C2 |
STRAIN OF HYBRID CULTURING Rattus norvegicus 122H9 CELLS WHICH IS PRODUCER OF CROSS-REACTIVE NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST PATHOGENIC FOR HUMAN ORTHOPOXVIRUSES | 2004 |
|
RU2281327C2 |
RECOMBINANT PLASMID VECTOR PVEAL-M12B9CH PROVIDING STABLE EXPRESSION AND SECRETION OF CHIMERIC MONOCLONAL ANTIBODY M12B9CH AGAINST ORTHOPOXVIRUSES IN MAMMALIAN CELLS AND RECOMBINANT CHIMERIC MONOCLONAL SCFV-FC ANTIBODY M12B9CH OBTAINED USING SPECIFIED VECTOR PVEAL-M12B9CH | 2021 |
|
RU2790134C1 |
AMIDES CONTAINING ADAMANTANE AND AROMATIC MOIETIES USED AS INHIBITORS OF ORTHOPOXVIRUS REPRODUCTION | 2021 |
|
RU2798665C2 |
RECOMBINANT STRAIN L-IVP 1421ABJCN POX VIRUS VIRULENCE GENES WITH BROKEN A56R, B8R, J2R, C3L, N1L FOR PRODUCING LIVE CULTURE OF ATTENUATED SMALLPOX VACCINE AND OTHER ORTHOPOXVIRUSES, PATHOGENIC FOR HUMANS | 2015 |
|
RU2588388C1 |
AMIDES WHICH COMBINE ADAMANTANE AND MONOTERPENE FRAGMENTS USED AS ORTHOPOXVIRUS INHIBITORS | 2019 |
|
RU2712135C1 |
RECOMBINANT PLASMID DNA pcL37 ENCODING POLYPEPTIDE WITH PROPERTIES OF HUMAN LIGHT CHAIN OF ANTIBODY AGAINST SMALLPOX VIRUS VACCINE, RECOMBINANT PLASMID DNA pcH37 ENCODING POLYPEPTIDE WITH PROPERTIES OF HEAVY CHAIN OF INDICATED ANTIBODY AND THEIR USING | 2006 |
|
RU2317330C2 |
MEDICATED PRODUCT FOR SMALLPOX VIRUS AND METHOD FOR PRODUCING AND USING IT | 2013 |
|
RU2543338C1 |
Authors
Dates
2014-05-20—Published
2013-01-10—Filed