TRANSGENE FOR PREPARING THE RECOMBINANT POLYPEPTIDE IN TRANSGENIC COW MILK, A METHOD OF OBTAINING THE TRANSGENIC COW (VARIANTS), MILK FROM TRANSGENIC COW, FOOD COMPOSITION Russian patent published in 1997 - IPC

FIELD: molecular biology. SUBSTANCE: transgene has at least one sequence for expression regulation, secretory DNA-sequence encoding secretory signal and recombinant DNA-sequence encoding recombinant polypeptides. Method of preparing transgenic cows involves incorporation of the above indicated transgene in embryonal cell - "target" of cow, transplantation of this cell to recipient and identification of at least one newborn heifer who is able to produce recombinant polypeptide. Milk obtained from the transgenic cow contains recombinant polypeptide. Food composition has transgenic milk containing recombinant polypeptide produced by transgenic cow. EFFECT: improved method of preparing. 35 cl, 5 tbl, 25 dwg