FIELD: pharmacology.
SUBSTANCE: group of inventions refers to a new clathrate complex of N-carbamoylmethyl-4-phenyl-2-pyrrolidone or 4-phenylpyracetam with cyclodextrin at a molar ratio of 1:1 to 1:10, respectively, and to versions of the method for its preparation, a composition comprising the said clathrate complex in an effective amount together with a pharmaceutically acceptable filler and/or excipient and a drug in the form of capsules, pills or an injection solution based on such a clathrate complex.
EFFECT: preparation of stable complexes with high solubility in water.
9 cl, 8 ex, 1 tbl, 7 dwg
Title |
Year |
Author |
Number |
PHARMACEUTICAL COMPOSITION AND MEDICINAL AGENT BASED ON CLATHRATE COMPLEX OF 7-BROM-5-(ORTHO-CHLOROPHENYL)-2,3-DIHYDRO-1H-1,4-BENZODIAZEPIN-2-ONE AND CYCLODEXTRIN, METHODS FOR PRODUCING IT (VERSIONS) |
2014 |
- Ismagilov Iskandar Khaliullovich
|
RU2570382C1 |
CLATRATE COMPLEX OF CYCLODEXTRINE OR ARABINOGALACTANE WITH 9-PHENYL-SYMM-OCTAHYDROSELENOXANTENE, ITS PRODUCTION METHOD (VERSIONS), PHARMACEUTICAL COMPOSITION AND MEDICATION |
2011 |
- Podgorodnichenko Vladimir Konstantinovich
- Tsyb Anatolij Fedorovich
- Roziev Rakhimdzhan Akhmetdzhanovich
- Goncharova Anna Jakovlevna
- Vorob'Ev Il'Ja Vladimirovich
- Erimbetov Kenes Tagaevich
|
RU2451680C1 |
β-CYCLODEXTRINE CLATHRATE COMPLEX WITH 5-HYDROXY-4-AMINOMETHYL-1 -CYCLOHEXYL(OR CYCLOHEPTYL)-3-ALKOXYCARBONYLINDOLE DERIVATIVE, METHOD FOR PREPARING IT (VERSIONS), PHARMACEUTICAL COMPOSITION AND DRUG |
2011 |
- Vorob'Ev Il'Ja Vladimirovich
- Khomichenok Viktor Vladimirovich
- Podgorodnichenko Vladimir Konstantinovich
- Tsyb Anatolij Fedorovich
- Roziev Rakhimdzhan Akhmetdzhanovich
- Goncharova Anna Jakovlevna
|
RU2464042C1 |
CLATHRATE COMPLEXES OF BETA-CYCLODEXTRIN WITH 1-{[6-BROMO-1-METHYL-5-METHOXY-2-PHENYLTHIOMETHYL-1-H-INDOL-3-YL]CARBONYL}-4-BENZYLPIPERAZINE, HAVING ANTIVIRAL ACTIVITY, SYNTHESIS AND USE THEREOF |
2010 |
- Vorob'Ev Il'Ja Vladimirovich
- Khomichenok Viktor Vladimirovich
- Podgorodnichenko Vladimir Konstantinovich
- Tsyb Anatolij Fedorovich
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|
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PHARMACEUTICAL COMPOSITION IN FORM OF SOLUTION FOR INJECTION AND METHOD FOR PRODUCTION THEREOF |
2013 |
- Kul'Kin Sergej Nikolaevich
|
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CLATHRATE COMPLEX OF ARABINOGALACTAN OR ARABIC GUM WITH 20-HYDROXYECDYSONES, METHOD FOR PRODUCING IT (VERSIONS), PHARMACEUTICAL COMPOSITION AND MEDICINAL PRODUCT |
2013 |
- Roziev Rakhimdzhan Akhmetdzhanovich
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- Podgorodnichenko Vladimir Konstantinovich
|
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