HETEROARYLAMINES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 1997 - IPC

FIELD: organic chemistry. SUBSTANCE: products: heteroarylamines of the formula (I) $$$ where A - benzyl; $$$ - benzyl or alkylthiazolylalkyl; $$$ and $$$ - hydrogen, $$$-alkyl, phenyl, $$$ or $$$-(O)-NH-groups; X - nitrogen or CH; Y - O, S or $$$; $$$ - H, $$$-alkyl, $$$-phenyl; n = 1-4; q = 1 or 2; Z - oxygen. Reagent 1: compound of the formula (II) $$$. Reagent 2: compound of the formula (III) $$$. Reaction condition: in the presence of base. The synthesized compounds were used in medicine as inhibitors of acetylcholine esterase. EFFECT: improved method of synthesis. 6 cl, 2 tbl