FIELD: organic chemistry. SUBSTANCE: products: piperidylmethyl-substituted derivatives of chroman of the formula (I) where A - hydrogen or lower alkoxy; E - hydrogen, hydroxyl, phenyl or piperidyl; G - unsubstituted phenyl or phenyl substituted with halogen and/or trifluoromethyl, phenoxy-group substituted with trifluoromethyl, benzyl, substituted phenylcarbonyl, aminocarbonyl at condition that E does not mean hydrogen or hydroxyl when G - phenyl, and their salts with inorganic acids. Reagent 1: compound of the formula (II) where X - halogen or hydroxyl. Reagent 2: compound of the formula (III). Reaction conditions: in inert solvent in the presence of base. Compounds of formulas I, II and III were given in description of invention. The synthesized compounds were used in medicine, in neurology. EFFECT: improved method of synthesis. 2 cl, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| HETEROCYCLYLMETHYL CHROMAN AS MIXTURE OF ISOMERS OR INDIVIDUAL ISOMERS OR SALTS THEREOF | 1992 |
|
RU2089549C1 |
| DERIVATIVES OF QUINOLINE-2-YL-METHOXYBENZYLHYDROXYUREA, METHOD OF SYNTHESIS AND 4-(QUINOLINE-2-YL-METHOXY)PHENYL-CYCLOALKYLKETONE AS A PARENTAL COMPOUND FOR SYNTHESIS OF QUINOLINE-2-YL-METHOXYBENZYLHYDROXYUREA DERIVATIVES | 1992 |
|
RU2048466C1 |
| DERIVATIVES OF 2,3-DIHYDROPYRANO[2,3-B]PYRIDINE OR THEIR SALT, METHOD OF SYNTHESIS OF 2-AMINOMETHYL-2,3-DIHYDROPYRANO[2,3-B]PYRIDINE AS PARENTAL SUBSTANCE FOR SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDROPYRANO[2,3-B]PYRIDINE AND A METHOD OF ITS SYNTHESIS | 1992 |
|
RU2044737C1 |
| DERIVATIVES OF QUINOLINE CARBOXYLIC ACID, MIXTURE OF ISOMERS OR INDIVIDUAL ISOMERS, THEIR PHARMACEUTICALLY ACCEPTABLE HYDRATES AND SALTS, METHOD FOR THEIR PRODUCTION | 1992 |
|
RU2077533C1 |
| DERIVATIVES OF 1,4-DIHYDROPYRIDINE, MIXTURES OF THEIR ISOMERS OR SEPARATE ISOMERS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND 2-CHLORO-3-CYANOBENZALDEHYDE | 1994 |
|
RU2155751C2 |
| DERIVATIVES OF CYCLOALKANOPYRIDINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND INTERMEDIATE COMPOUNDS | 1997 |
|
RU2194698C2 |
| METHODS FOR PREPARATION OF 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DERIVATIVES IN THE FORM OF R ISOMERS AND THEIR SALTS, STARTING SUBSTANCES AND INTERMEDIATES FOR PREPARATION THEREOF | 1995 |
|
RU2155752C2 |
| DERIVATIVES OF 7-ISOINDOLINYLQUINOLONE AND 7-ISOINDOLINYLNAPHTHYRIDONE | 1993 |
|
RU2111964C1 |
| DERIVATIVES OF QUINOXALINEDIONE, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL AGENT BASED ON SAID | 1994 |
|
RU2140420C1 |
| DERIVATIVES OF BENZOFURANYLALKANE CARBOXYLIC ACID OR A MIXTURE OF THEIR ISOMERS, OR SEPARATE ISOMERS, OR THEIR SALTS | 1994 |
|
RU2125564C1 |
