AMINO ACID DERIVATIVES, METHOD OF PRODUCING SAID DERIVATIVES, USE THEREOF AND PHARMACEUTICAL COMPOSITION Russian patent published in 2010 - IPC C07C229/34 C07C229/36 C07C227/12 C07C271/22 A61K31/195 A61K31/198 A61P7/00 A61P37/00 

FIELD: chemistry.

SUBSTANCE: described is a compound of formula I , where R₁ is C₁-C₆alkyl; R₂ is a radical of formula a, where R₆ is C₁-C₁₂alkyl, R₇ is H, X is O, R₃ is -A-B-COOH, where A and B each independently represents a chemical bond, or CDE, where D and E each independently represents H, and each R₄ and R₅ independently represents H, under the condition that, if R₄ is H, R₅ is H, R₃ is COOH, R₂ is a radical of formula a, and R₇ is H, R₁ is CH₃, and XR₆ is an unsubstituted OC₁-C₁₂alkyl radical, then XR₆ is not in the meta-position to (CH₂)₂-CR₁R₃(NR₄R₅), in free form or in form of a pharmaceutically acceptable salt, as well a production method and use thereof primarily during transplantation, as well as pharmaceutical composition containing said compounds.

EFFECT: new compounds have useful biological properties.

7 cl, 3 ex